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In particular, angiogenic cytokines, such as vascular endothelial growth factor A (VEGFA) and interleukin 8 (IL8), promoted human umbilical vein endothelial cell (HUVEC) vascular formation in vitro

ECL3 and the top of TM7 are tilted slightly away from the peptide, adopting a marginally more open TM bundle than observed in AMYRs

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